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. 2024 Jul 16;39(9):2053–2066. doi: 10.1093/humrep/deae154

Table 2.

Correlation between energy metabolism and embryonic development in patients with normal or abnormal ovarian function.

Metabolic parameters Normal ovarian function (n = 21)
Ovarian infertility (n = 64)
Fertilization rate (%) On time Day 3 (%) Blastocyst (%) Fertilization rate (%) On time Day 3 (%) Blastocyst (%)
FAO function
 FAO function 0.122 0.105 0.064 −0.317 * −0.056 −0.149
 Maximal FAO function 0.031 0.109 0.262 −0.171 0.133 0.025
 FAO function for ATP production 0.130 0.367 0.131 −0.298 * −0.021 −0.111
Glycolytic function
 Glycolysis −0.034 0.046 0.244 −0.316 * −0.120 −0.229
 Glycolytic capacity 0.010 0.116 0.220 −0.290 * −0.101 −0.223
 Glycolytic reserve −0.147 0.618 * 0.055 −0.095 0.129 −0.122
 Glycolytic reserve (%) −0.075 0.620 * 0.030 0.046 0.214 −0.011
Mitochondrial function
 Basal respiration −0.089 0.180 0.102 −0.272 * 0.166 0.125
 ATP production 0.023 0.188 0.077 −0.263 * 0.214 0.164
 Maximal respiration 0.035 0.134 0.027 −0.210 0.236 0.184
 Spare respiratory capacity 0.025 0.061 0.012 −0.096 0.206 0.161
 Proton leak −0.205 0.342 0.151 −0.266 * 0.120 0.043
 Coupling efficiency (%) 0.570 * −0.391 −0.122 0.102 0.068 0.112
ATP production rate
 Total ATP production 0.038 0.096 −0.050 −0.368 ** −0.009 −0.028
 Mitochondrial ATP (%) −0.163 0.063 0.161 −0.078 0.162 0.358 **
 Glycolytic ATP (%) 0.163 −0.063 −0.161 0.078 −0.162 −0.358 **

Bold numbers indicate significant correlations.

*

P < 0.05.

**

P < 0.01.