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. 2024 Aug 7;86(9):5024–5033. doi: 10.1097/MS9.0000000000002429

Table 8.

Cox regression analysis between two groups

Variable adjusted Unadjusted hazards ratio (95% CI) P Adjusted hazards ratio (95% CI) P
Lateral to medial 0.90 (0.48–1.72) 0.760 0.95 (0.44–2.04) 0.897
 Age at diagnosis 1.03 (1.01–1.06) 0.019 1.05 (1.01–1.08) 0.007
 Sex (female vs. male) 1.07 (0.59–1.91) 0.833 0.93 (0.45–1.94) 0.851
 BMI 1.02 (0.96–1.08) 0.627 1.01 (0.95–1.08) 0.666
 Tumour location 0.93 (0.83–1.03) 0.144 0.93 (0.81–1.06) 0.284
 Operation mode (lap vs. open) 0.74 (0.29–1.87) 0.534 0.68 (0.23–2.01) 0.489
 Operation Duration 1.00 (0.98–1.01) 0.879 1.01 (0.99–1.02) 0.269
Lateral to medial 0.90 (0.48–1.72) 0.760 0.95 (0.44–2.04) 0.897
 Right-sided resections 1.63 (0.91–2.94) 0.102
 Left-sided resections 1.27 (0.54–2.99) 0.589
 Anorectal resections 0.56 (0.29–1.05) 0.069
Lateral to medial 0.90 (0.48–1.72) 0.760 0.79 (0.41–1.55) 0.504
 CIBH 1.65 (0.90–3.01) 0.104 1.77 (0.92–3.39) 0.089
 Rectal bleeding 0.91 (0.48–1.73) 0.772 0.86 (0.43–1.72) 0.664
 Abdominal pain 1.77 (0.91–3.43) 0.091 1.22 (0.55–2.69) 0.621
 IDA 1.12 (0.57–2.20) 0.753 1.19 (0.59–2.42) 0.629
 Weight loss 2.01 (0.94–4.32) 0.073 1.59 (0.70–3.65) 0.265
 Constipation 1.10 (0.34–3.56) 0.869 0.69 (0.19–2.46) 0.574
 Bowel obstruction 4.03 (1.44–11.26) 0.008 3.35 (0.99–11.27) 0.051
Lateral to medial 0.90 (0.48–1.72) 0.760 0.96 (0.49–1.84) 0.891
 Hypertension 0.99 (0.55–1.78) 0.976 1.04 (0.56–1.93) 0.899
 Diabetes mellitus 0.59 (0.21–1.65) 0.317 0.57 (0.19–1.63) 0.290
 Asthma 1.74 (0.69–4.41) 0.243 1.79 (0.70–4.61) 0.223
 COPD 3.00 (1.34–6.73) 0.008 2.93 (1.23–6.63) 0.010
 Atrial Fibrillation 2.11 (0.75–5.89) 0.156 1.98 (0.68–5.79) 0.212
 Heart failure 1.34 (0.33–5.54) 0.685 1.33 (0.29–6.05) 0.710
Lateral to medial 0.90 (0.48–1.72) 0.760 0.79 (0.39–1.57) 0.503
 Non-adenocarcinoma 1.00
 Adenocarcinoma 1.45 (0.35–5.98) 0.609 1.06 (0.23–4.89) 0.939
Grade of differentiation
 Well 1.00
 Moderate 0.88 (0.34–2.28) 0.795 0.65 (0.24–1.74) 0.389
 Poor 2.73 (0.95–7.87) 0.063 1.34 (0.43–4.16) 0.615
Dukes stage
 A 1.00
 B 0.88 (0.27–2.84) 0.825 0.54 (0.11–2.67) 0.447
 C 3.93 (1.38–11.2) 0.011 0.98 (0.11–9.10) 0.987
 D 8.73 (2.17–35.02) 0.002 3.32 (0.26–42.15) 0.355
T stage
 T1 1.00
 T2 0.69 (0.16–3.11) 0.634 0.82 (0.17–3.90) 0.804
 T3 1.50 (0.45–5.01) 0.510 1.37 (0.27–6.91) 0.705
 T4 4.46 (1.29–15.31) 0.018 2.52 (0.47–13.59) 0.281
N stage
 N0 1.00
 N1 3.28 (1.60–6.73) 0.001 1.72 (0.32–9.35) 0.532
 N2 7.26 (3.49–15.05) <0.001 3.00 (0.51–17.65) 0.224
M stage
 M0 1.00
 M1 3.90 (1.74–8.75) <0.001 0.89 (0.27–2.98) 0.859
R malignancy
 R0 1.00
 R1 2.59 (0.63–10.69) 0.189 1.31 (0.29–6.00) 0.731

CIBH, change in bowel habits; COPD, chronic obstructive pulmonary disease; IDA, iron deficiency anaemia.