Table 8.
Cox regression analysis between two groups
Variable adjusted | Unadjusted hazards ratio (95% CI) | P | Adjusted hazards ratio (95% CI) | P |
---|---|---|---|---|
Lateral to medial | 0.90 (0.48–1.72) | 0.760 | 0.95 (0.44–2.04) | 0.897 |
Age at diagnosis | 1.03 (1.01–1.06) | 0.019 | 1.05 (1.01–1.08) | 0.007 |
Sex (female vs. male) | 1.07 (0.59–1.91) | 0.833 | 0.93 (0.45–1.94) | 0.851 |
BMI | 1.02 (0.96–1.08) | 0.627 | 1.01 (0.95–1.08) | 0.666 |
Tumour location | 0.93 (0.83–1.03) | 0.144 | 0.93 (0.81–1.06) | 0.284 |
Operation mode (lap vs. open) | 0.74 (0.29–1.87) | 0.534 | 0.68 (0.23–2.01) | 0.489 |
Operation Duration | 1.00 (0.98–1.01) | 0.879 | 1.01 (0.99–1.02) | 0.269 |
Lateral to medial | 0.90 (0.48–1.72) | 0.760 | 0.95 (0.44–2.04) | 0.897 |
Right-sided resections | 1.63 (0.91–2.94) | 0.102 | ||
Left-sided resections | 1.27 (0.54–2.99) | 0.589 | ||
Anorectal resections | 0.56 (0.29–1.05) | 0.069 | ||
Lateral to medial | 0.90 (0.48–1.72) | 0.760 | 0.79 (0.41–1.55) | 0.504 |
CIBH | 1.65 (0.90–3.01) | 0.104 | 1.77 (0.92–3.39) | 0.089 |
Rectal bleeding | 0.91 (0.48–1.73) | 0.772 | 0.86 (0.43–1.72) | 0.664 |
Abdominal pain | 1.77 (0.91–3.43) | 0.091 | 1.22 (0.55–2.69) | 0.621 |
IDA | 1.12 (0.57–2.20) | 0.753 | 1.19 (0.59–2.42) | 0.629 |
Weight loss | 2.01 (0.94–4.32) | 0.073 | 1.59 (0.70–3.65) | 0.265 |
Constipation | 1.10 (0.34–3.56) | 0.869 | 0.69 (0.19–2.46) | 0.574 |
Bowel obstruction | 4.03 (1.44–11.26) | 0.008 | 3.35 (0.99–11.27) | 0.051 |
Lateral to medial | 0.90 (0.48–1.72) | 0.760 | 0.96 (0.49–1.84) | 0.891 |
Hypertension | 0.99 (0.55–1.78) | 0.976 | 1.04 (0.56–1.93) | 0.899 |
Diabetes mellitus | 0.59 (0.21–1.65) | 0.317 | 0.57 (0.19–1.63) | 0.290 |
Asthma | 1.74 (0.69–4.41) | 0.243 | 1.79 (0.70–4.61) | 0.223 |
COPD | 3.00 (1.34–6.73) | 0.008 | 2.93 (1.23–6.63) | 0.010 |
Atrial Fibrillation | 2.11 (0.75–5.89) | 0.156 | 1.98 (0.68–5.79) | 0.212 |
Heart failure | 1.34 (0.33–5.54) | 0.685 | 1.33 (0.29–6.05) | 0.710 |
Lateral to medial | 0.90 (0.48–1.72) | 0.760 | 0.79 (0.39–1.57) | 0.503 |
Non-adenocarcinoma | 1.00 | |||
Adenocarcinoma | 1.45 (0.35–5.98) | 0.609 | 1.06 (0.23–4.89) | 0.939 |
Grade of differentiation | ||||
Well | 1.00 | |||
Moderate | 0.88 (0.34–2.28) | 0.795 | 0.65 (0.24–1.74) | 0.389 |
Poor | 2.73 (0.95–7.87) | 0.063 | 1.34 (0.43–4.16) | 0.615 |
Dukes stage | ||||
A | 1.00 | |||
B | 0.88 (0.27–2.84) | 0.825 | 0.54 (0.11–2.67) | 0.447 |
C | 3.93 (1.38–11.2) | 0.011 | 0.98 (0.11–9.10) | 0.987 |
D | 8.73 (2.17–35.02) | 0.002 | 3.32 (0.26–42.15) | 0.355 |
T stage | ||||
T1 | 1.00 | |||
T2 | 0.69 (0.16–3.11) | 0.634 | 0.82 (0.17–3.90) | 0.804 |
T3 | 1.50 (0.45–5.01) | 0.510 | 1.37 (0.27–6.91) | 0.705 |
T4 | 4.46 (1.29–15.31) | 0.018 | 2.52 (0.47–13.59) | 0.281 |
N stage | ||||
N0 | 1.00 | |||
N1 | 3.28 (1.60–6.73) | 0.001 | 1.72 (0.32–9.35) | 0.532 |
N2 | 7.26 (3.49–15.05) | <0.001 | 3.00 (0.51–17.65) | 0.224 |
M stage | ||||
M0 | 1.00 | |||
M1 | 3.90 (1.74–8.75) | <0.001 | 0.89 (0.27–2.98) | 0.859 |
R malignancy | ||||
R0 | 1.00 | |||
R1 | 2.59 (0.63–10.69) | 0.189 | 1.31 (0.29–6.00) | 0.731 |
CIBH, change in bowel habits; COPD, chronic obstructive pulmonary disease; IDA, iron deficiency anaemia.