Table 1.

Assessment tools for hidradenitis suppurativa.

Assessment tool	Advantages	Disadvantages
1. Hurley27–33	Simple to use and provides rapid classification.	It is ineffective for assessing therapy responses.
2. The Hidradenitis Suppurativa Clinical Response (HiSCR)34–36	A valid, responsive, and meaningful endpoint for assessing the treatment effectiveness of HS in both clinical research and daily practice.	Its application is limited to evaluating treatment responses. HiSCR may lack sensitivity for milder cases due to its requirement of at least three abscesses and inflammatory nodules at baseline. Does not take draining tunnels into account in a dynamic manner, which can lead to an incomplete evaluation of the treatment response.
3. Modified Sartorius Score2,37,38	Dynamic scoring system that can detect changes in clinical disease severity.	Time-consuming, especially for patients with a wide-spread illness.
4. Physician Global Assessment Tool for HS (HS-PGA)38–40	Quick and simple assessment tool. Frequently used in clinical practice and clinical trials.	Largely dependent on the clinician’s capacity to identify essential lesions of HS.
5. The Hidradenitis Suppurativa Severity Index (HSSI)38,39	It is simple and rapid, utilizing subjective and objective criteria, and can assess disease severity without the need to differentiate between distinct elementary lesions. It also evaluates body surface area, drainage, and pain severity.	Lacks validation and lacks detail compared to the modified Sartorius score.
6. The International Hidradenitis Suppurativa Severity (IHS4) and IHS4-5536,39,41–43	It is a validated score that provides a dynamic assessment of HS severity in both clinical practice and the clinical trial setting.	Time-consuming due to the need for counting individual lesions, and individual lesion counts were demonstrated to differ between raters when compared to patients with milder forms of the disease.

HS, hidradenitis suppurativa.