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Trained immunity induced by BCG vaccine. BCG: Bacille Calmette–Guérin; H3K27ac: Acetylation of lysine 27 at histone 3; H3K4m3: Trimethylation of lysine 4 at histone 3; H3K9m3: Trimethylation of lysine 9 at histone 3; HSPC: Hematopoietic stem cells and progenitor cells; IL-1β: Interleukin-1 beta; IL-6: Interleukin-6; TNF-α: Tumor necrosis factor-alpha.
