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. 2024 Aug 7;633(8028):137–146. doi: 10.1038/s41586-024-07769-3

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© The Author(s) 2024

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Extended Data Fig. 2 — a, Copy number variation subtypes were called by facetsSuite. RNA expression level (TPM Log2FC) in samples with gains or losses of the driver gene were compared with that of wild-type samples (*FDR < 0.05, ** FDR < 0.01, *** FDR < 0.001, Two-sided Wilcoxon Rank Sum Test). b, Structural variants affecting driver genes (top) and DNA damage repair genes (bottom). Circos plots with counts (middle ring) for deletions (yellow), inversions (blue), tandem-duplications (green) and translocations (grey), displayed by gene and chromosomal location. CNV, copy number variation; LOH, loss of heterozygosity; cnLOH, copy number neutral LOH; ampLOH, amplification LOH.