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. 2024 Sep 4;30(9):e70030. doi: 10.1111/cns.70030

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© 2024 The Author(s). CNS Neuroscience & Therapeutics published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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The effects of rh‐B4galt1 on ferroptosis via the TAZ/Nrf2/HO‐1 signaling pathway. (A–F) Representative Western blotting images and quantitative analysis of the levels of TAZ, Nrf2, HO‐1, GPX4 and SLC7A11. (G) The iron concentration in the brain tissue. *p < 0.05 versus siNC group; ^# p < 0.05 versus Rh‐B4galt1+siNC group. (H–L) Western blotting was carried out to test the expression of Nrf2, HO‐1, GPX4, and SLC7A11. (M) The iron concentration in the brain tissue. *p < 0.05 versus PBS group; ^# p < 0.05 versus Rh‐B4galt1 group. Data are expressed as mean ± SD, n = 6 for each group.