Extended Data Fig. 1. Additional characterization of metabolites in PTER-KO mice.
Related to Fig. 3. a, Urine N-acetyltaurine concentration (left) and taurine concentration (right) of 13- to 14-week-old male WT or PTER-KO mice. N = 5/group. b, Representative extracted ion chromatograms of synthetic N-acetyltaurine and N-propionyltaurine standards and endogenous peaks of blood plasma from 14-week old wild-type male mice without taurine water supplementation. c, Plasma of N-propionyltaurine levels of 13 to 14-week-old male WT or PTER-KO mice on high fat diet and after taurine water supplementation (2.5% w/v). N = 5/group. Data are shown as mean ± SEM. In a, P-values were calculated from two-tailed unpaired t-tests.