Table 1.
Study | Country | No. of patients | No. of CRT patients | Criteria of LPN metastasis | Pathologic positive rate (%) | |
---|---|---|---|---|---|---|
Fujita et al. [13] (2009) | Japan | 210 | 6 | >5 mm | 22.4 | |
Ogawa et al. [15] (2016) | Japan | 272 | - | ≥5 mm in the SA | 17.0 | |
Yamaoka et al. [16] (2017) | Japan | 19 | - | ≥5 mm in the SA | 36.8 | |
Matsuda et al. [17] (2018) | Japan | 45 | - | ≥8 mm in the SA | 21.9 | |
Dev et al. [18] (2018) | India | 43 | - | ≥8 mm in the SA | 20.9 | |
Iwasa et al. [19] (2021) | Japan | 69 | - | >7 mm in the SA | 15.7 | |
Abe et al. [20] (2022) | Japan | 67 | 7 | ≥5 mm in the SA | 26.9 | |
Oh et al. [22] (2014) | Korea | 66 | 66 | >5 mm in the SA | 33.3 | |
Akiyoshi et al. [23] (2015) | Japan | 77 | 77 | ≥7 mm in the LA | 40.3 | |
Sinukumar et al. [24] (2015) | Japan | 8 | 8 | ≥8 mm in the SA | 25.0 | |
Shin et al. [25] (2016) | USA | 18 | 18 | ≥7 mm in the LA | 61.1 | |
Ishihara et al. [26] (2017) | Japan | 31 | 31 | ≥8 mm in the SA | 51.6 | |
Kim et al. [27] (2017) | Korea | 53 | 53 | ≥5 mm in the SA | 37.7 | |
Kim et al. [28] (2018) | Korea | 57 | 57 | ≥5 mm in the SA | 40.4 | |
Hiyoshi et al. [29] (2020) | Japan | 78 | 26 | >5 mm | 11.5 | |
Kawai et al. [30] (2021) | Japan | 42 | 42 | >8 mm | 52.4 | |
Song et al. [31] (2021) | Korea | 99 | 99 | ≥5 mm in the SA | 30.3 | |
Agger et al. [32] (2021) | Sweden | 344 | 309 | <5 mm in the SA with 3 malignant featuresa or 5–9 mm in the SA with 2 malignant featuresa | 8.7 |
LPN, lateral pelvic lymph node; CRT, chemoradiotherapy; SA, short axis; LA, long axis.
Malignant features of lymph nodes were defined as indistinct borders, heterogeneous signal, or attenuation and round shape.