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. 2024 Aug 14;3(9):101208. doi: 10.1016/j.jacadv.2024.101208

Table 4.

Age and Sex Determine Differences in 10-Yr Risk of Developing Cardiometabolic Cardiovascular Risk Factors

Predictor Age Groups
Sex Groups
Age < Mediana
Age ≥ Mediana
Interaction with Ageb
Femalec
Malec
Interaction With Sexd
10-Year Risk of Developing ≥1 CVDRFs
OR (95% CI) P Value OR (95% CI) P Value P Value OR (95% CI) P Value OR (95% CI) P Value P Value
Depression 1.472 (1.311-1.653) <0.001 1.128 (1.012-1.256) 0.029 <0.001 1.597 (1.452-1.757) <0.001 1.396 (1.195-1.631) <0.001 0.002
Anxiety 1.504 (1.336-1.693) <0.001 1.120 (1.004-1.249) 0.043 <0.001 1.665 (1.510-1.836) <0.001 1.488 (1.272-1.742) <0.001 0.002
Anxiety and/or Depression 1.596 (1.441-1.769) <0.001 1.200 (1.091-1.319) <0.001 <0.001 1.785 (1.637-1.945) <0.001 1.467 (1.285-1.675) <0.001 <0.001

Boldface values represent statistical significance (P < 0.05).

CVDRF = cardiometabolic cardiovascular risk factor.

a

All analyses are adjusted for sex and for the other components of the primary model (pre-existing CVDRFs, lifestyle factors, and smoking).

b

The interaction terms = predictor∗age [≥versus <median].

c

All analyses are adjusted for age and for the other components of the primary model (pre-existing CVDRFs, lifestyle factors, and smoking).

d

Interaction term = predictor∗sex. Lifestyle factors: body mass index, insomnia, and physical activity. CVDRFs: hypertension, hyperlipidemia, diabetes mellitus.