Table 3.
Associations between demographic variables and mortality risk among systemic lupus erythematosus cases from enrollment*
| Univariate analysis | Adjusting for age, sex, race, and blood sample | |||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| n | Died, % | HR | 95% CI | HR | 95% CI | |
|
| ||||||
| Age (per year) | 265 | 1.03 | 1.00–1.05 | 1.03 | 1.01–1.06 | |
| Sex | ||||||
| Male | 25 | 28 | 2.3 | 0.96–5.7 | 2.2 | 0.90–5.6 |
| Female | 240 | 10 | 1.0 | Referent | 1.0 | Referent |
| Race† | ||||||
| African American | 160 | 14 | 1.6 | 0.72–3.6 | 2.2 | 0.92–5.2 |
| Whites | 89 | 10 | 1.0 | Referent | 1.0 | Referent |
| Lupus nephritis | ||||||
| Present | 63 | 17 | 1.5 | 0.71–3.2 | 2.1 | 0.92–4.7 |
| Absent | 202 | 10 | 1.0 | Referent | 1.0 | Referent |
| Anti-dsDNA antibodies‡ | ||||||
| Present | 62 | 18 | 2.1 | 0.96–4.7 | 2.7 | 1.2–6.2 |
| Absent | 176 | 9 | 1.0 | Referent | 1.0 | Referent |
| Provided blood sample | ||||||
| No | 21 | 29 | 3.4 | 1.4–8.2 | 3.5 | 1.4–8.6 |
| Yes | 244 | 11 | 1.0 | Referent | 1.0 | Referent |
*
See Table 2 for definitions.
†
Sixteen patients who were American Indian, Asian, or Hispanic were excluded from these analyses.
‡
Among the 244 with blood samples, 6 were missing anti-dsDNA antibody data because of inadequate sample.