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Initiation of shelterin core complex (B) Tpp1 disruption, inactivation of (A) Pot1 and (F) Rap1 expression in isolated lung tissue after ITI exposure to 2.0 mg/rat of MMA-SS welding fume (n = 4–6; values are means ± standard error; *significantly different from MMA-SS groups). (C) Tin2, (D) Trf1 and (E) Trf2 expression remained unchanged in lung cDNA.
