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. 2024 Aug 20;9(35):37288–37298. doi: 10.1021/acsomega.4c05060

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© 2024 The Authors. Published by American Chemical Society

Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).

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Pyronaridine⁴⁷ and several other drugs²²⁻²⁸ in clinical use (benznidazole and nifurtimox) and others that are in development to treat Chagas disease that have been tested in vivo in the mouse model to date as further described in the text.