Table 2.
Investigation of factors affecting treatment discontinuation rate (Cox proportional hazards modeling)
| Factor | Univariate | Multivariable | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | p value | HR | 95% CI | p value | ||
| CP-equivalent dose | ≥ 1000 mg | 1.624 | 0.940–2.806 | 0.0820 | 1.826 | 1.042–3.199 | 0.0353 |
| Sex | Female | 1.135 | 0.851–1.514 | 0.3882 | 1.164 | 0.872–1.555 | 0.3022 |
| Duration of disease | ≥ 6 years | 0.740 | 0.528–1.037 | 0.0806 | 0.692 | 0.488–0.981 | 0.0387 |
| PANSS total score | ≥ 80 | 0.984 | 0.729–1.329 | 0.9151 | 1.055 | 0.776–1.436 | 0.7313 |
CI confidence interval, CP chlorpromazine, HR hazard ratio, PANSS Positive and Negative Syndrome Scale