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. Author manuscript; available in PMC: 2024 Sep 5.
Published in final edited form as: J Bone Miner Res. 2019 Dec 30;35(4):698–713. doi: 10.1002/jbmr.3929

Figure 5.

Figure 5.

iOB methylation status changes. (A) Decreased methylation peak in osteogenic marker Bglap3, Bglap2 and Ibsp locus. Visualization of regions was done by Integrative Genomics Viewer (IGV). Included tracks are rms (relative methylation score) for different groups. (B) Heatmap of mean rms values of differentially methylated regions (DMRs) in iOB versus fibroblast across samples. Each row represents a differentially methylated region. Each column represents a cell type. (C) The number of genes associated with differentially methylated regions (DMRs) is respected to the number of differentially expressed genes in iOB versus fibroblast.