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. 2024 Sep 5;4(9):e0003631. doi: 10.1371/journal.pgph.0003631

Table 4. Sociodemographic, obstetric, and antenatal factors associated with anaemia at 36 weeks of gestation.

Variables Frequency distribution Logistic regression analyses
Total Anaemia Univariate analysis Multivariate analysis
N N (%) COR (95%CI) p-value AOR (95%CI) p-value
Sociodemographic variables
Age group (years)
    16–25 38 21 (55.3) 0.63 (0.32–1.24) 0.182
    26–35 340 149 (43.8) 1
    36–46 44 21 (47.7) 0.85 (0.46–1.60) 0.642
Marital status
    Single 30 16 (53.3) 0.70 (0.33–1.47) 0.349
    Married 389 173 (44.5) 1
    Widowed 3 2 (66.7) 0.40 (0.04–4.45) 0.456
Education level
    No education 182 86 (47.3) 1.27 (0.71–2.26) 0.417
    Primary 58 25 (43.1) 1.50 (0.73–3.09) 0.268
    Junior high 62 33 (55.2) 1
    Senior high 76 29 (38.2) 1.84 (0.93–3.64) 0.078
    Tertiary 44 18 (40.9) 1.64 (0.75–3.59) 0.212
Ethnicity
    Dagomba 340 166 (48.8) 1 1
    Gonja 22 6 (27.3) 2.54 (0.97–6.66) 0.057 1.89 (0.66–5.45) 0.236
    Frafra 34 10 (29.4) 2.29 (1.06–4.93) 0.034 1.96 (0.88–4.40) 0.102
    Others (Asante, Ewe, Kusasi) 26 9 (34.6) 1.80 (0.78–4.15) 0.167 1.64 (0.66–4.09) 0.289
Religion
    Islam 372 173 (46.5) 1
    Christianity 49 17 (34.7) 1.64 (0.87–3.04) 0.121
    Traditional 1 1 (100) ---- ----
Occupation
Unemployed 153 77 (50.3) 0.80 (0.53–1.20) 0.284
Informal 228 102 (44.7) 1
Formal 41 12 (29.3) 1.95 (0.95–4.03) 0.068
Socioeconomic status
    High 168 60 (35.7) 1.27 (0.75–2.14) 0.376 1.23 (0.70–2.13) 0.471
    Middle 84 40 (47.6) 1 1
    Low 170 91 (53.5) 2.07 (1.34–3.21) 0.001 1.78 (1.10–2.90) 0.020
Household food security level
    Food secure 329 150 (45.6) 0.66 (0.39–1.20) 0.185
    Mild/moderate food insecure 63 23 (36.5) 1
    Severe food insecure 30 18 (60.0) 0.38 (0.16–0.94) 0.085
Obstetric and antenatal variables
Number of pregnancies
    0–1 111 52 (46.9) 0.89 (0.56–1.39) 0.594
    ≥ 2–4 251 110 (43.8) 1
    ≥ 5 60 29 (48.3) 0.84 (0.47–1.47) 0.528
Number of deliveries
    0–1 120 55 (45.8) 0.93 (0.60–1.45) 0.758
    ≥ 2–4 247 109 (44.1) 1
    ≥ 5 55 27 (49.1) 0.82 (0.46–1.47) 0.504
Frequency of antenatal contacts
    < 8 304 147 (48.4) 1 1
    ≥ 8 118 44 (37.3) 0.64 (0.41–0.98) 0.041 0.80 (0.50–1.30) 0.378
Pre-pregnancy body mass index (BMI)
    Underweight (BMI < 18.5 kg/m2) 13 7 (53.8) 0.84 (0.27–2.56) 0.758 0.84 (0.25–2.80) 0.783
    Normal (BMI 18.5–24.9 kg/m2) 279 138 (49.5) 1 1
    Overweight/obese (BMI ≥ 25 kg/m2) 130 46 (35.4) 1.79 (1.16–2.75) 0.008 1.62 (1.01–2.58) 0.041
Sulphadoxine-pyrimethamine intake
    None 25 17 (68.0) 2.13 (1.40–3.26) <0.001 2.22 (1.40–3.51) 0.001
    1–3 doses 249 126 (50.6) 1 1
    > 3 doses 148 48 (32.4) 0.48 (0.20–1.16) 0.103 0.56 (0.22–1.42) 0.227
Tetanus-diphtheria immunization
    No 31 19 (61.3) 1
    Yes 391 172 (44.0) 2.01 (0.95–4.26) 0.067
Insecticide-treated bed nets use
    No 152 74 (48.7) 1
    Yes 270 117 (43.3) 1.24 (0.83–1.85) 0.289
Family planning use before current pregnancy
    No 347 165 (47.6) 1 1
    Yes 75 26 (34.7) 1.71 (1.02–2.87) 0.044 1.57 (0.22–1.43) 0.122
Iron folic acid supplementation
    No 7 5 (71.4) 1
    Yes 415 186 (44.8) 3.08 (0.59–16.0) 0.182
Malaria infection during pregnancy
    No 363 153 (42.2) 1 1
    Yes 59 38 (64.4) 2.48 (1.40–4.40) 0.002 3.14 (1.66–5.93) <0.001
Previous history of anaemia
    No 394 178 (45.2) 1
    Yes 28 13 (46.4) 0.95 (0.44–2.05) 0.898
Type of antenatal provider
    Health centre 228 101 (44.3) 1
    Hospital 194 90 (46.4) 0.92 (0.63–1.34) 0.667
Ever received education on anaemia
    No 14 9 (64.3) 1
    Yes 408 182 (44.6) 2.23 (0.74–6.79) 0.156
Maternal knowledge on anaemia
    Inadequate 124 57 (46.0) 1
    Adequate 298 134 (45.0) 1.04 (0.68–1.59) 0.851

p-value < 0.05 Regression model (R2:0.396; p<0.001) COR: crude odds ratio AOR: adjusted odds ratio Bold AOR, 95%CI, p-value: significant values for associated factors