Table.

Relative risk of Achilles tendon disorders associated with use of fluoroquinolones according to age

	Cases	Controls	Crude relative risk (95% CI)	Adjusted relative risk (95% CI)*
All Achilles tendon disorders
Age <60:	(n=423)	(n=6058)
No use	308	4387	1.0	1.0
Current use	13	174	1.1 (0.6 to 1.9)	0.9 (0.5 to 1.6)
Recent use	19	240	1.1 (0.7 to 1.8)	1.0 (0.6 to 1.7)
Past use	83	1257	0.9 (0.7 to 1.2)	0.9 (0.7 to 1.1)
Age ⩾60:	(n=319)	(n=3942)
No use	211	2797	1.0	1.0
Current use	33	124	3.5 (2.3 to 5.3)	3.2 (2.1 to 4.9)
Recent use	15	182	1.1 (0.6 to 1.9)	1.0 (0.6 to 1.7)
Past use	60	839	0.9 (0.7 to 1.3)	0.8 (0.6 to 1.1)
Achilles tendon ruptures
Age <60:	(n=21)	(n=6058)
No use	18	4387	1.0	1.0
Current use	—	174	—	—
Recent use	—	240	—	—
Past use	3	1257	0.6 (0.2 to 2.0)	0.6 (0.2 to 2.0)
Age ⩾60:	(n=17)	(n=3942)
No use	8	2797	1.0	1.0
Current use	3	124	8.4 (2.2 to 32.2)	7.1 (1.7 to 29.1)
Recent use	2	182	3.8 (0.8 to 18.2)	3.5 (0.7 to 17.3)
Past use	4	839	1.7 (0.5 to 5.5)	1.4 (0.4 to 4.8)
Achilles tendinitis
Age <60:	(n=402)	(n=6058)
No use	290	4387	1.0	1.0
Current use	13	174	1.1 (0.6 to 2.0)	1.0 (0.5 to 1.8)
Recent use	19	240	1.2 (0.7 to 1.9)	1.1 (0.7 to 1.8)
Past use	80	1257	1.0 (0.7 to 1.2)	0.9 (0.7 to 1.2)
Age ⩾60:	(n=302)	(n=3942)
No use	203	2797	1.0	1.0
Current use	30	124	3.3 (2.2 to 5.1)	3.1 (2.0 to 4.8)
Recent use	13	182	1.0 (0.6 to 1.8)	0.9 (0.5 to 1.6)
Past use	56	839	0.9 (0.7 to 1.2)	0.8 (0.6 to 1.1)

^*Adjusted for sex, age, visits to general practitioner, calendar year, use of corticosteroid, history of musculoskeletal disorders, and obesity.