Figure 2. IL6 and TNF-α methylation profile in oral cells of the study population (n=85). (A) Methylation frequency for IL6. (B) Representative bands showing IL6 MSP reactions. (C) Representative bands showing the specificity of IL6 MSP reactions. (D) Methylation frequency for TNF-α. (E) Representative bands showing TNF-α MSP reactions. (F) Representative bands showing the specificity of TNF-α MSP reactions.

L: DNA ladder; bp: base pair; M: methylated; U: unmethylated; C+: fully methylated DNA; C-: fully unmethylated DNA; OM: oral mucositis. Note: methylated and unmethylated profiles are also known as partially methylated. Methylated profile is also known as hypermethylated. Unmethylated profile is also known as hypomethylated.