Figure 2. Oral leukoplakia. A, Non-flat, white plaque exhibiting sharp and well-defined borders in a 34-year-old man. B, Epithelium with a brightly eosinophilic keratin surface showing architectural and cytological changes of dysplasia (hematoxylin & eosin [H&E], 200×). C, Severe dysplasia showing loss of basal cell polarization, budding rete ridges, increased hyperchromasia (*), and mitotic figures (arrows) confined to the basal and parabasal layers (H&E, 400×).
