Table 1.
Demographic and biologic characteristics of studied patients
| Characteristics | Non-survivors (n = 53) | Survivors (n = 31) | Statistic value | P-value |
|---|---|---|---|---|
| Age group, n (%) | ||||
| < 5 years old | 40 (75.5) | 18 (58.1) | 2.01 (1) | 0.155a |
| ≥ 5 years old | 13 (24.5) | 13 (41.9) | ||
| Gender, n (%) | ||||
| Male | 33 (62.3) | 25 (80.6) | 2.92 (1) | 0.13a |
| Female | 20 (37.7) | 6 (19.4) | ||
| Main diagnosis, n (%) | 0.011b | |||
| Sepsis | 31 (58.5) | 13 (41.9) | 2.14 (1) | 0.143a |
| Cardiovascular diseases | 8 (15.1) | 13 (41.9) | 7.51 (1) | 0.006a |
| Respiratory diseases | 2 (3.8) | 3 (9.7) | – | 0.353b |
| Other | 12 (22.6) | 2 (6.5) | 3.69 (1) | 0.055a |
| Required mechanical ventilation, n (%) | ||||
| Yes | 50 (94.3) | 20 (64.5) | 10.47 (1) | 0.001a |
| No | 3 (5.7) | 11 (35.5) | ||
| Required vasoactive agents, n (%) | ||||
| Yes | 48 (90.6) | 20 (64.5) | 7.00 (1) | 0.008a |
| No | 5 (9.4) | 11 (35.5) | ||
| Organ dysfunction, n (%) | ||||
| Neurology | 30 (56.6) | 0 (0.0) | 24.88 (1) | < 0.001a |
| Respiratory | 52 (98.1) | 25 (80.6) | – | 0.009b |
| Cardiovascular | 48 (90.6) | 25 (80.6) | – | 0.314b |
| Haematology | 33 (62.3) | 17 (54.8) | 0.192 (1) | 0.661a |
| Gastroenterology | 9 (17) | 2 (6.5) | – | 0.201b |
| Hepatology | 4 (7.6) | 1 (3.2) | – | 0.647b |
| Nephrology | 3 (5.7) | 0 (0.0) | – | 0.293b |
| GCS, mean (SD) | 6.2 (2.8) | 11.7 (2.5) | −9.16 (70.31) | < 0.001c |
| Platelet count, × 109/L Median (IQR) | 113.0 (22.5–299.0) | 257.0 (24.0–403.0) | −1.24 | 0.214d |
| Leucocyte count, × 109/L Median (IQR) | 13.0 (5.5–19.2) | 7.1 (4.8–18.0) | −1.09 | 0.272d |
| Lactate, mmol/L Median (IQR) | 7.1 (4.6–13.3) | 4.0 (2.6–5.5) | −3.68 | < 0.001d |
| D-dimer, μg/mL Median (IQR) | 4.7 (1.9–12.2) | 1.1 (0.8–2.2) | −4.19 | < 0.001d |
Notes: GCS = Glasgow Coma Scale; SD = standard deviation; IQR = interquartile range.
a
Chi-square test for independence, with χ2-statistic (df) value;
b
Fisher’s exact test;
c
independent t-test, with t-statistic (df) value;
d
Mann-Whitney U test, with Z-statistic value.
All comparisons were made between the non-survivors and survivors groups