Extended Data Fig. 5. ABEGO-based loop geometries and amino acid sequence preferences of the cluster that each HLH motif belongs to.
(Left) The 18 representative HLH motifs are shown as in Extended Data Fig. 3. (Middle) ABEGO torsion patterns of the loop. This result suggests that the relative arrangements of adjacent helices strongly limit the torsion patterns of the connecting loop. (Right) Amino acid sequence preferences of each HLH motif. The first residue of the loop is indicated by an arrow.