Fig. 5.

Comparison of early versus late onset of therapy in typical CIDP patients. A The start of the first therapy after first symptom manifestation is depicted in months: early onset of therapy was defined as start of first therapy up to 12 months after first manifestation of symptoms. Late start of therapy was set as start of first therapy more than 12 months after first manifestation of symptoms. B, C Mean INCAT arm and leg disability scores ± SEM at diagnosis (0), after 12, 24 and 36 months, respectively. Data was available from (early/late start of therapy) 85/80 (at diagnosis), 60/73 (after 12 months), 49/64 (after 24 months) and 43/59 (after 36 months) patients. A p-value ≥ 0.05 was classified as not significant, p < 0.05 (*) as significant, p < 0.01 (**), p < 0.001 (***), and p < 0.0001 (****) as highly significant. For a better clarity, not all significant results are shown. CIDP chronic inflammatory demyelinating polyneuropathy, INCAT inflammatory neuropathy cause and treatment, SEM standard error of the mean