Table 2.
Diagnostic data of CIDP patients
| Characteristic | Typical CIDP | CIDP variants |
|---|---|---|
| Reflexes (n (%)) | ||
| Areflexia | 142 (72) | 26 (60) |
| Hyporeflexia | 51 (26) | 6 (14) |
| Normal reflexes | 0 (0) | 8 (19) |
| Hyperreflexia | 0 (0) | 0 (0) |
| Not available | 4 (2) | 3 (7) |
| Cerebrospinal fluid | ||
| CSF cell number (mean ± SEM in cell/µl) | 4 ± 1 | 2 ± 0.2 |
| CSF protein level (mean ± SEM in mg/dl) | 94 ± 7 | 67 ± 10 |
| Albuminocytological dissociation (n (%)) | 116 (79) | 16 (60) |
| Not available | 36 (18) | 16 (37) |
| Neurography (n (%)) | ||
| Demyelinating | 68 (35) | 11 (26) |
| Axonal | 6 (3) | 2 (5) |
| Axonal-demyelinating | 120 (62) | 28 (65) |
| Not available | 3 (2) | 2 (5) |
| Motor nerve conduction criteriaa | ||
| In > 2 nerves | 178 (92) | 35 (81) |
| In 1 nerve | 13 (7) | 5 (12) |
| None | 0 | 0 |
| Not available | 6 (3) | 3 (7) |
| Sensory nerve conduction criteriaa | ||
| In > 2 nerves | 156 (81) | 26 (60) |
| In 1 nerve | 34 (18) | 9 (21) |
| None | 0 | 5 (12) |
| Not available | 7 (4) | 3 (7) |
| Biopsy of N. suralis (n (%)) | ||
| Not available | 126 (65) | 18 (42) |
| Pathologica | 66 (34) | 22 (51) |
| Normal | 5 (3) | 3 (7) |
| Blood values | ||
| HbA1c (mean ± SEM in %) | 5.8 ± 0.1 | 5.7 ± 0.1 |
| CK level (mean ± SEM in U/l) | 180 ± 14 | 191 ± 24 |
| ANA elevated (n (%)) | 17 (9) | 3 (7) |
| ANCA elevated (n (%)) | 2 (1) | 1 (2) |
| Renal parameters elevated (n (%)) | 23 (12) | 3 (7) |
| Liver parameters elevated (n (%)) | 23 (12) | 7 (16) |
Acquired clinical and diagnostic data of CIDP patients, subdivided into typical CIDP and CIDP variants. Results are shown as absolute values including their relative percentages or as mean ± SEM
ANA antinuclear antibody, ANCA anti-neutrophil cytoplasmatic antibody, CIDP chronic inflammatory demyelinating polyneuropathy, CK creatine kinase, CSF cerebrospinal fluid, HbA1c hemoglobin A1C, SEM standard error of the mean
aAccording to EAN/PNS guidelines form 2021 [11]