Table 1.
Participant demographics
| Characteristic | Total n = 8771 (%) | Initiation n = 4533 (%) | Switching n = 5165 (%) |
|---|---|---|---|
| Gender | |||
| F | 6,222 (71%) | 3,150 (69%) | 3,747 (73%) |
| M | 2,549 (29%) | 1,383 (31%) | 1,418 (27%) |
| Age category (years) | |||
| 0–20 | 326 (3.7%) | 257 (5.7%) | 147 (2.8%) |
| 21–30 | 1,682 (19%) | 1,130 (25%) | 841 (16%) |
| 31–40 | 2,556 (29%) | 1,386 (31%) | 1,455 (28%) |
| 41–50 | 2,318 (26%) | 1,011 (22%) | 1,490 (29%) |
| 51–60 | 1,392 (16%) | 520 (11%) | 944 (18%) |
| > 60 | 497 (5.7%) | 229 (5.1%) | 288 (5.6%) |
| Country | |||
| Australia | 2,512 (29%) | 1,293 (29%) | 1,414 (27%) |
| Turkey | 1,991 (23%) | 927 (20%) | 1,346 (26%) |
| Italy | 706 (8.0%) | 442 (9.8%) | 352 (6.8%) |
| Spain | 590 (6.7%) | 288 (6.4%) | 364 (7.0%) |
| Kuwait | 559 (6.4%) | 353 (7.8%) | 244 (4.7%) |
| Iran | 429 (4.9%) | 163 (3.6%) | 294 (5.7%) |
| Croatia | 309 (3.5%) | 234 (5.2%) | 121 (2.3%) |
| Belgium | 267 (3.0%) | 150 (3.3%) | 161 (3.1%) |
| Tunisia | 103 (1.2%) | 74 (1.6%) | 47 (0.9%) |
| Japan | 94 (1.1%) | 70 (1.5%) | 43 (0.8%) |
| Netherlands | 87 (1.0%) | 37 (0.8%) | 59 (1.1%) |
| Other* | 497 (5.7%) | 274 (6.0%) | 273 (5.3%) |
| MS course | 1,293 (29%) | ||
| Relapsing remitting | 7,610 (87%) | 3,906 (86%) | 4,570 (88%) |
| Secondary progressive | 537 (6.1%) | 113 (2.5%) | 443 (8.6%) |
| Primary progressive | 303 (3.5%) | 253 (5.6%) | 66 (1.3%) |
| Progressive relapsing | 95 (1.1%) | 60 (1.3%) | 42 (0.8%) |
| Radiologically isolated syndrome | 4 (< 0.1%) | 3 (< 0.1%) | 2 (< 0.1%) |
| Clinically isolated syndrome | 222 (2.5%) | 198 (4.4%) | 42 (0.8%) |
| EDSS | 2.4 (1.9%) | 2.0 (1.7%) | 2.6 (2.0%) |
| Relapse count (in previous 24 months) | |||
| 0 | 4,708 (54%) | 2,016 (44%) | 3,005 (58%) |
| 1 | 2,847 (32%) | 1,790 (39%) | 1,478 (29%) |
| 2 | 918 (10%) | 570 (13%) | 498 (9.6%) |
| 3 | 228 (2.6%) | 126 (2.8%) | 137 (2.7%) |
| 4 | 46 (0.5%) | 23 (0.5%) | 28 (0.5%) |
| 5 | 16 (0.2%) | 7 (0.2%) | 12 (0.2%) |
| 6 | 3 (< 0.1%) | 1 (< 0.1%) | 2 (< 0.1%) |
| 7 | 4 (< 0.1%) | - | 4 (< 0.1%) |
| 10 | 1 (< 0.1%) | - | 1 (< 0.1%) |
| Disease duration (years) | 8.2 (8.3%) | 4.4 (6.7%) | 10.6 (8.3%) |
*See appendix for full list of countries