Values of IC50 (μg mL−1) of newly developed anticancer agents against MCF-7 and MCF-10A cell lines, as compared to a clinical anticancer drug (5-FU).
Cells | IC50 (μg mL−1) ± SD | ||||
---|---|---|---|---|---|
PAHMQ | CoPAHMQ | CuPAHMQ | ZnPAHMQ | 5-FU | |
MCF-7 | 19.79 ± 0.31 | 25.79 ± 0.32 | 11.18 ± 0.39 | 23.83 ± 0.18 | 28.34 ± 1.89 |
MCF-10A | 101.29 ± 0.58 | 149.37 ± 2.1 | 59.97 ± 0.06 | 128.84 ± 2.32 | 41.03 ± 1.89 |
SI | 5.11 | 5.79 | 5.63 | 5.40 | 1.45 |