Table 4.

Key findings regarding quality of life in GO patients.

Clinical feature	Key findings
Depression	Depression is a significant predictor of impaired QoL in GO patients (13, 21, 73, 74)
Anxiety	Anxiety is not a unique contributor to QoL in GO patients (21)
Age	Older age is associated with lower vision-related QoL (12, 21)
Appearance-related social anxiety and social avoidance	Appearance-related social anxiety and social avoidance contribute to appearance-related QoL (21, 78)
Female gender	Female GO patients report more appearance-related problems compared to male patients (12)
Exopthalmos	Exopthalmos is equally prevalent in patients with high and low QoL (72)
Diplopia	Significant relation between diplopia and QoL (72, 74)
Orbital decompression surgery	Improves appearance-related and vision-related QoL (17, 18, 20, 82, 83, 84, 85)
Strabismus surgery	Improves appearance-related and vision-related QoL (17, 18, 20, 82, 83, 84, 85)
Radiotherapy	Improves vision-related QoL (17, 83)
Eyelid lenghtening and blepharoplasty	Improves appearance-related QoL (17, 83)
Steroid treatment	Improves appearance-related and vision-related QoL (20, 84)