. 2024 Aug 7;5(3):e230090. doi: 10.1530/RAF-23-0090
This work is licensed under a Table 2.
Baseline characteristics of study participants with and without endometriosis (UK Biobank). Data are presented as mean ± s.d. or as n (%).
| Controls | Endometriosis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall | Self-reported | Hospital records | Surgically confirmed | Severe cases | ||||||||
| Value | P | Value | P | Value | P | Value | P | Value | P | |||
| Participants, n | 6331 | 1537 | 716 | 1152 | 1294 | 337 | ||||||
| Age (years)a | 45.20 ± 2.88 | 44.53 ± 2.87 | <0.001* | 44.50 ± 2.85 | <0.001* | 44.46 ± 2.85 | <0.001* | 44.49 ± 2.87 | <0.001* | 44.44 ± 2.83 | <0.001* | |
| Age group (years)b | <0.001* | <0.001* | <0.001* | <0.001* | <0.001* | |||||||
| ≤42.5 | 1345 (21.2) | 451 (29.3) | 207 (28.9) | 348 (30.2) | 380 (29.4) | 102 (30.3) | ||||||
| 42.5–45 | 2055 (32.5) | 514 (33.4) | 246 (34.4) | 388 (33.7) | 446 (34.5) | 116 (34.4) | ||||||
| 45–47.5 | 1258 (19.9) | 286 (18.6) | 128 (17.9) | 209 (18.1) | 233 (18.0) | 59 (17.5) | ||||||
| 47.5–50 | 1673 (26.4) | 286 (18.6) | 135 (18.9) | 207 (18.0) | 235 (18.2) | 60 (17.8) | ||||||
| Waist : hip ratioa | 0.805 ± 0.068 | 0.798 ± 0.067 | 0.001* | 0.797 ± 0.063 | 0.002* | 0.798 ± 0.068 | 0.004* | 0.799 ± 0.066 | 0.010* | 0.797 ± 0.067 | 0.032* | |
| WHR groupb | 0.003* | 0.025* | 0.005* | 0.014* | 0.024* | |||||||
| ≤0.75 | 1449 (22.9) | 378 (24.6) | 171 (23.9) | 288 (25.0) | 318 (24.6) | 87 (25.8) | ||||||
| 0.75–0.80 | 1774 (28.0) | 481 (31.3) | 226 (31.6) | 359 (31.2) | 397 (30.7) | 108 (32.1) | ||||||
| 0.80–0.85 | 1608 (25.4) | 351 (22.8) | 179 (25.0) | 259 (22.5) | 299 (23.1) | 74 (22.0) | ||||||
| >0.85 | 1496 (23.6) | 326 (21.2) | 140 (19.6) | 245 (21.3) | 279 (21.6) | 67 (19.9) | ||||||
| BMI (kg/m²)a | 26.96 ± 5.56 | 26.48 ± 4.89 | <0.001* | 26.30 ± 4.89 | <0.001* | 26.57 ± 4.84 | 0.015* | 26.60 ± 4.90 | 0.020* | 26.69 ± 4.92 | 0.33 | |
| BMI group (kg/m²)b | 0.20 | 0.029* | 0.09 | 0.66 | 0.84 | |||||||
| ≤22.5 | 1255 (19.8) | 292 (19.0) | 153 (21.4) | 198 (17.2) | 233 (18.0) | 52 (15.4) | ||||||
| 22.5–25 | 1493 (23.6) | 402 (26.2) | 185 (25.8) | 305 (26.5) | 339 (26.2) | 97 (28.8) | ||||||
| 25–30 | 2118 (33.5) | 534 (34.7) | 239 (33.4) | 414 (35.9) | 454 (35.1) | 119 (35.3) | ||||||
| >30 | 1454 (23.0) | 307 (20.0) | 138 (19.3) | 234 (20.3) | 266 (20.6) | 69 (20.5) | ||||||
| Smoking habitc | 0.45 | 0.17 | 0.61 | 0.80 | 0.23 | |||||||
| Never smokers | 2965 (46.8) | 702 (45.7) | 312 (43.6) | 542 (47.1) | 600 (46.4) | 175 (51.9) | ||||||
| Current smokers | 472 (7.5) | 125 (8.1) | 58 (8.1) | 97 (8.4) | 100 (7.7) | 21 (6.2) | ||||||
| Past smokers | 1007 (15.9) | 257 (16.7) | 129 (18.0) | 184 (16.0) | 215 (16.6) | 47 (14.0) | ||||||
| Exogenous hormonec | <0.001* | <0.001* | 0.002* | <0.001* | 0.031* | |||||||
| HRT | 73 (1.2) | 26 (1.7) | 15 (2.1) | 15 (1.3) | 23 (1.8) | 5 (1.5) | ||||||
| Oral contraceptive pill | 353 (5.6) | 138 (9.0) | 94 (13.1) | 95 (8.3) | 109 (8.4) | 30 (8.9) | ||||||
| None of the two above | 5905 (93.3) | 1373 (89.3) | 607 (84.8) | 1042 (90.5) | 1162 (89.8) | 302 (89.6) | ||||||
| Hay fever seasonc | 0.52 | 0.15 | 1.00 | 0.95 | 0.26 | |||||||
| Yes | 4018 (63.5) | 962 (62.6) | 435 (60.8) | 731 (63.5) | 820 (63.4) | 224 (66.5) | ||||||
| No | 2313 (36.5) | 575 (37.4) | 281 (39.3) | 421 (36.6) | 474 (36.6) | 113 (33.5) | ||||||
| Asthmac | 0.26 | 0.98 | 0.53 | 0.44 | 0.22 | |||||||
| Yes | 1064 (16.8) | 240 (15.6) | 120 (16.8) | 185 (16.1) | 206 (15.9) | 48 (14.2) | ||||||
| No | 5267 (83.2) | 1297 (84.4) | 596 (83.2) | 967 (83.9) | 1088 (84.1) | 289 (85.8) | ||||||
| Eczemac | 0.97 | 0.28 | 0.37 | 0.63 | 0.64 | |||||||
| Yes | 232 (3.7) | 56 (3.6) | 32 (4.5) | 36 (3.1) | 51 (3.9) | 14 (4.2) | ||||||
| No | 6099 (96.3) | 1481 (96.4) | 684 (95.5) | 1116 (96.9) | 1243 (96.1) | 323 (95.9) | ||||||
*P values <0.05 were considered as evidence of a significant difference between comparison groups.
aP values were derived from t-tests; bP values for trend were derived from logistic regression models; cP values were derived from chi-square tests.
HRT, hormone replacement therapy.