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. 2022 Dec 8;11:38. doi: 10.1186/s13750-022-00289-5

Table 2.

Criteria for assessing study validity

Low susceptibility to bias High susceptibility to bias Risk of bias type
Study design
 Comparison domain Comparison across both space and time (e.g., BACI) Comparison across space or time only (e.g., CI, BA) Selection
 Control matching at study initiation (not applicable to BA studies, where control and intervention take place at the same site) Well-matched control and intervention sites, close in proximity or clearly similar, but without spillover effects Well-matching not evident, other factors likely to influence difference between treatment and control sites Selection
 Effect modifiers and confounding factors during study period No or minimal presence of co-interventions, co-exposures or trends present that are likely to differ between groups, baseline environmental conditions similar to intervention period; or if present, confounding factors are accounted for Co-interventions, co-exposures or trends present that are likely to differ between groups, e.g., differing climate conditions, weather events, or other environmental or anthropogenic changes; and factors are not accounted for Performance
Groundwater measurements
 Measurement similarity and representativeness Similar and representative measurements across groups, unlikely to differ systematically Systematic differences in measurements, outcomes not assessed similarly, or measurements unlikely to be representative Detection
Other
 Confounding variables not included in other risk of bias types (e.g., funding source) No obvious confounding factors, or confounding factors present but accounted for Confounding factors stated or obviously present but not accounted for Other