Table 2.
Laboratory parameters of the DN and non-DN groups
| DN group | Non-DN group | P | |
|---|---|---|---|
| Mean ± standard deviation | |||
| Leukocyte count (k/mm3) | 6.9 ± 2 | 6.8 ± 2.3 | 0.33 |
| Hemoglobin (g/dL) | 13.1 ± 1.6 | 13.5 ± 1.7 | 0.16 |
| Hematocrit (%) | 39 ± 4 | 40 ± 5 | 0.27 |
| Platelet count (k/mm3) | 262 ± 36 | 256 ± 34 | 0.35 |
| Aspartate transaminase (U/L) | 24 ± 9 | 28 ± 10 | 0.68 |
| Alanine transaminase (U/L) | 23 ± 11 | 22 ± 12 | 0.65 |
| Median (min.-max.) | |||
| C-reactive protein (mg/L) | 9.5 (1–250) | 2.2 (0.1–26.1) | <0.001 |
| Serum albumin (g/dL) | 4.3 (2.8–5.3) | 4.4 (2.9–5.6) | 0.01 |
| Fasting plasma glucose (mg/dL) | 177 (66–565) | 147 (65–514) | <0.001 |
| HbA1c (%) | 8.3 (4.9–16.5) | 7.7 (5.1–17.2) | 0.001 |
| Blood urea (mg/dL) | 34 (17–222) | 32 (13–258) | 0.14 |
| Serum creatinine (mg/dL) | 0.83 (0.59–3.41) | 0.8 (0.39–3.93) | 0.049 |
| eGFR (%) | 99.5 (15.3–185) | 99.8 (15.8–181) | 0.057 |
| Serum uric acid (mg/dL) | 5.6 (1.8–10.4) | 5.5 (2.4–13.6) | 0.07 |
| Triglyceride (mg/dL) | 153 (47–850) | 151 (50–856) | 0.36 |
| Total cholesterol (mg/dL) | 187 (52–318) | 200 (50–378) | 0.14 |
| LDL-cholesterol (mg/dL) | 132 (21–200) | 114 (29–244) | 0.03 |
| HDL-cholesterol (mg/dL) | 46 (13–87) | 44 (17–92) | 0.1 |
| CAR | 2.19 (0.2–49) | 0.56 (0.02–5.8) | <0.001 |
Bold values indicate statistical significance. DN: Diabetic neuropathy; LDL: Low-density lipoprotein; HDL: High-density lipoprotein; CAR: C-reactive protein to albumin ratio; eGFR: Estimated glomerular filtration rate.