Table 3.
Laboratory parameters of the DN and non-DN patients in the subgroup cohort
| DN group | Non-DN group | P | ||
|---|---|---|---|---|
| Gender, n (%) | Women | 56 (73) | 151 (51) | 0.001 |
| Men | 21 (27) | 144 (49) | ||
| Absent | 212 (79.7) | 402 (93.3) | ||
| Median (min.-max.) | ||||
| Age (years) | 62 (47–76) | 56 (29–81) | <0.001 | |
| Weight (kg) | 86 (68–117) | 85 (58–123) | 0.33 | |
| Waist circumference (cm) | 114 (88–132) | 106 (82–137) | <0.001 | |
| BMI (kg/m2) | 35.7 (24–46.3) | 30.8 (21–46) | <0.001 | |
| Diabetes duration (years) | 7 (1–21) | 3 (1–20) | <0.001 | |
| Leukocyte count (k/mm3) | 6.6 (3.7–9.7) | 6.5 (3.7–9.9) | 0.57 | |
| Hemoglobin (g/dL) | 13.7 (12.5–15.9) | 13.4 (12.2–17) | 0.96 | |
| Hematocrit (%) | 39 (36–47) | 40 (35–51) | 0.24 | |
| Platelet count (k/mm3) | 246 (168–479) | 232 (138–423) | 0.83 | |
| C-reactive protein (mg/L) | 12 (1–67) | 2.7 (0.1–19) | <0.001 | |
| Serum albumin (g/dL) | 4.4 (3.1–5) | 4.4 (3.3–5.6) | 0.15 | |
| Fasting plasma glucose (mg/dL) | 136 (100–459) | 143 (70–514) | 0.68 | |
| HbA1c (%) | 7.1 (6.3–12.8) | 7.4 (5.1–15.9) | 0.23 | |
| Blood urea (mg/dL) | 32 (17–167) | 36 (23–198) | 0.23 | |
| Serum creatinine (mg/dL) | 0.8 (0.7–1.2) | 0.79 (0.4–0.9) | 0.43 | |
| eGFR (%) | 103 (35–125) | 109 (44–145) | 0.44 | |
| Triglyceride (mg/dL) | 153 (77–850) | 160 (50–856) | 0.72 | |
| Total cholesterol (mg/dL) | 162 (131–200) | 202 (50–244) | 0.02 | |
| LDL-cholesterol (mg/dL) | 132 (21–200) | 114 (29–244) | <0.001 | |
| HDL-cholesterol (mg/dL) | 46 (13–87) | 44 (17–92) | 0.12 | |
| Aspartate transaminase (U/L) | 19 (7–58) | 19 (8–53) | 0.32 | |
| Alanine transaminase (U/L) | 16 (6–43) | 20 (6–64) | 0.15 | |
| CAR | 2.7 (0.2–14.6) | 0.6 (0.02–4.4) | <0.001 | |
Bold values indicate statistical significance. DN: Diabetic neuropathy; BMI: Body mass index; LDL: Low-density lipoprotein; HDL: High-density lipoprotein; CAR: C-reactive protein to albumin ratio; eGFR: Estimated glomerular filtration rate.