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. 2024 Sep 6;19(9):e0309802. doi: 10.1371/journal.pone.0309802

Table 5. Matrix effect and recovery of donepezil (DPZ) in rat plasma (n = 6).

SD and CV stand for standard deviation and coefficient of variation, respectively.

Nominal concentration of DPZ (ng/mL) Recovery
(mean ± SD, %)
Matrix effect
Mean ± SD (%) CV (%)
0.5 102.99± 4.74 98.81 ± 9.90 10.01
1.5 98.46 ± 8.30 103.75 ± 6.31 6.08
500 104.71 ± 3.30 100.40 ± 3.64 3.63
1,000 106.79 ± 2.98 92.17 ± 2.44 2.64