Title |
Objective response rate after 3 cycles of treatment, safety throughout the study period |
Number of patients screened |
32 |
Number of patients enrolled |
13 |
Number of patients evaluable for toxicity |
13 |
Number of patients evaluated for efficacy |
13 |
Evaluation method |
RECIST 1.1 |
Response assessment, CR |
5 (38.5%) |
Response assessment, PR |
5 (38.5%) |
Response assessment, SD |
3 (23.1%) |
Response assessment, PD |
0 (0%) |
Median duration assessment, PFS |
9.3 months (95% CI: 5.8-30.4 months) |
Median duration assessment, OS |
The median OS and its 95% CI could not be estimated because the estimated OS at the last time point of 49.3 months was >50%. |
Response duration |
12.8 months (95% CI: 1.4 to ≥28.5 months) |
Duration of treatment |
The median number of treatment cycles for combination therapy was 7 (range, 3-21) |