Table 2.
HS-GC-MS analytical conditions for analysis of impurities in hand sanitizers.
| Analytical System | |
|---|---|
| GC- MS | GCMS-QP2020 NX |
| Headspace Autosampler | HS−20 |
| Column | PoraBOND Q (25 m x 0.25 mm I.D., d.f. = 3 µm) |
| HS Parameters | |
| Oven Temperature | 85°C |
| Sample Line Temperature | 150°C |
| Transfer Line Temperature | 160°C |
| Injection Time | 1 min |
| Pressurizing Gas Pressure | 90 kPa |
| Equilibrating Time | 10 mins |
| Shaking Level | 2 |
| GC Cycle Time | 30 mins |
| GC Parameters | |
| Column temperature | 50°C |
| Injection Mode | Split mode |
| Split ratio 50 | |
| Carrier Gas | Helium |
| Gas Flow Condition | Constant linear velocity mode |
| Linear velocity 43.4 cm/s | |
| Oven Temperature Programming | 50°C (1 min) |
| → 20 °C/min to 250°C (9 mins) | |
| Column Flow | 1.19 mL/min |
| Injection Volume | 1.0 µL |
| MS Parameters | |
| Ion source temperature | 230°C |
| Interface temperature | 300°C |
| Measurement mode | Scan/SIM |
| Scan range | m/z 24–200 |
| MSD Solvent Delay | No solvent delay |
| MSD m/z Settings | Start time (0 min) |
| End Time (20 min) | |
| Acquisition mode (SIM/Scan) | |