Table 2.

System setup of MD simulations

	PS only sulfate up	PS only sulfate down	GABA + PS sulfate up	GABA + PS sulfate down
Simulation box	118 Å x 118 Å x 188 Å	118 Å x 118 Å x 188 Å	120 Å x 120 Å x 183 Å	120 Å x 120 Å x 183 Å
Number of atoms	269496	269496	268076	268076
Number of waters	62349	62349	61958	61958
Salt concentration	150 mM NaCl	150 mM NaCl	150 mM NaCl	150 mM NaCl
Number of lipids	186 POPC	186 POPC	186 POPC	186 POPC
	124 POPE	124 POPE	124 POPE	124 POPE
	26 POPS	26 POPS	26 POPS	26 POPS
	70 Cholesterol	70 Cholesterol	70 Cholesterol	70 Cholesterol
	20 Sphingomyelins	20 Sphingomyelins	20 Sphingomyelins	20 Sphingomyelins
	18 PIP2	18 PIP2	18 PIP2	18 PIP2