Table 5.

Interaction energy of hotspot residues considered with acarbose.

Residues	ΔEbinding	ΔEMM	ΔEpol	ΔEnpol
Asp69	−0.38	−0.22	−0.15	0
Tyr72	0.01	−0.12	0.12	0
His112	0.07	0.05	0.02	0
Lys156	2.87	−3.94	6.85	−0.08
Tyr158	−7.61	−12.26	5.46	−0.88
Phe159	−4.07	−4.61	0.92	−0.41
Phe178	−0.98	−1.06	0.19	−0.12
Arg213	1.39	1.62	−0.21	0
Asp215	−1.40	−1.06	−0.35	0