MIC2.

Methods	1988 to 1996 Randomised controlled trial
Participants	359 patients Stage information not known
Interventions	Supportive care versus supportive care and chemotherapy Cisplatin, mitomycin C, ifosphamide
Outcomes	Survival
Notes	—
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Stated as randomised in paper, checks run on IPD suggest adequate sequence generation
Allocation concealment (selection bias)	Low risk	Central randomisation
Incomplete outcome data (attrition bias) All outcomes	Low risk	Individual patient data obtained and checked for all outcomes
Selective reporting (reporting bias)	Low risk	Individual patient data obtained and checked for all outcomes
Other bias	Low risk	Study appears to be free of other sources of bias