Methods |
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Participants |
Country: China
Primary nephrotic syndrome patients (urinary protein > 3.5 g/24 h; plasma albumin < 30 g/dL; oedema and hypercholesterolaemia)
Number: treatment group (30); control group (28)
Age range: treatment group (5 to 42 years); control group (4 to 44 years)
Sex (M/F): treatment group (19/11); control group (17/11)
Exclusions: secondary nephrotic syndrome
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Interventions |
Treatment group
Control group
Prednisone
initial dose 1.0mg/kg/d. Dose was then reduced gradually 10% after 8 weeks.
When prednisone was ineffective or partially effective, CTX combined with methylprednisolone was used
|
Outcomes |
Plasma albumin
24 hours urine protein
Blood cholesterol
Blood triglyceride
Effective rate
|
Notes |
Baseline declining kidney function: NS
Remission: NS
Pathology: NS
Relapse: NS
Time to relapse: NS
Mean follow‐up: 6 months
Dosage: described in detail
Prepare method: NS
Source of funding: none
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