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Up-titration regimens for Marguerite RoAD OLE. MRI performed prior to each dose increase and then at regular intervals. Implementation of dosing algorithms in case of ARIA findings. ARIA, amyloid-related imaging abnormalities; APOE ɛ4, apolipoprotein E ɛ4 allele; MRI, magnetic resonance imaging; OLE, open-label extension. Adapted from Bateman RJ, et al. Alz Res Therapy 14, 178 (2022) under the terms of the Creative Commons CC BY license https://creativecommons.org/licenses/by/4.0/.
