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. 2024 Aug 19;20(11):4532–4550. doi: 10.7150/ijbs.98856

Figure 6.

Figure 6

Effects of c-Ski on the proangiogenic effect of A2AR activation in HMECs. (A) Levels of c-Ski detected by western blots 24 h after treatment with different concentrations of CGS21680. ** p < 0.01, ##p <0.01, compared with the previous adjacent group (n = 3); NS, not significant. (B) Immunohistochemistry for c-Ski (green) in HMECs 24 h after CGS21680 treatment. Scale bar, 50 µm. (C) Changes in the CGS21680-induced increase in the intracellular protein level of c-Ski in HMECs after 24 h of c-Ski RNAi. ** p < 0.01, *p <0.05 (n = 3); NS, not significant. (D) Changes in CGS21680-induced cell proliferation for 24 h in HMECs after c-Ski RNAi. ** p < 0.01 (n = 9); NS, not significant. (E) Representative images of CGS21680-induced tube formation in HMECs after c-Ski RNAi treatment for 24 h. Scale bar, 50 µm. (F) Quantitative analysis of (E). **p < 0.01, *p <0.05 (n=5); NS, not significant.