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. 2024 Aug 19;20(11):4438–4457. doi: 10.7150/ijbs.98362

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Sleeve gastrectomy and dietary restriction enhance capacities of lipid metabolism in steatotic livers. (A) Technical scheme of the ambient mass spectrometry imaging metabolomics method. (B) H&E-stained rat liver sample section was mapped with the abundance of total metabolites in Sham, Sham + DR and SG groups. (C) Function enrichment of upregulated differentially generated metabolites (Sham + DR vs. Sham, SG vs. Sham and SG vs. Sham + DR) was analyzed based on the KEGG database. Abbreviations: Sham: sham surgery; DR: dietary restriction; SG: sleeve gastrectomy; KEGG: Kyoto encyclopedia of genes and genomes. The Fisher's exact test was performed. 'Adjusted p < 0.05' represents statistical significance.