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. 2024 Aug 12;20(11):4407–4423. doi: 10.7150/ijbs.95350

Figure 5.

Figure 5

Inhibition of pNFκB (nuclear factor κ B) expression by SAS and its role in the inhibition of PD-L1 expression by the tellurium compound. (A) Mouse B16/F10 cells either (B) were transfected with control plasmid or (C) overexpressing (OE) NFκB or (D) human VLA-4-positive AML cells isolated from AML patients, either (E) transfected with control plasmid or (F) overexpressing (OE) Akt or (H) overexpressing (OE) NFκB, were cultured on FN-coated plates with or without SAS for 24 hours. The cells were collected, fixed, permeabilized and stained for NFκB (A, D-F) or PD-L1 (B, C, G, H). The results show one representative of 3 experiments. NFκB (nuclear factor kappa-light-chain-enhancer of activated B cells).