Morton 1968.
Methods | Allocation: randomly assigned. Blinding: double, identical capsule given by the hospital pharmacist. "no one concerned with the care of patients knew which patients were started on placebo". Duration: 6 months. | |
Participants | Diagnosis: schizophrenia. N=40 (12 to relevant interventions). Age: 25‐55 yrs. Sex: all male. History: in hospital >2 yrs, on chlorpromazine >18 months, maintenance doses of tranquillizer had been administered for at least 18 months. | |
Interventions | 1. Chlorpromazine cessation: placebo. N=6. 2. Trifluoperazine cessation: placebo. N=14. 3. Chlorpromazine continuation: (dose not reported). N=6 4. Trifluoperazine continuation: (dose not reported). N=14. | |
Outcomes | Relapse.
Mental state: Wing scale. Unable to use ‐ Behaviour change: WPRS (no usable data). |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Unclear risk | B ‐ Unclear |