Table 1.
Mean neutralizing antibody titers after AZD7442 administration were obtained for each time point with the different SARS-CoV-2 variants tested.
| SARS-CoV-2 variant | Wild-type pVNT mean titer (titer dilution−1) | Alpha pVNT mean titer (titer dilution−1) | Beta pVNT mean titer (titer dilution−1) | Gamma pVNT mean titer (titer dilution−1) | Delta pVNT mean titer (titer dilution−1) | Omicron BA.4/5 pVNT mean titer (titer dilution−1) | XBB 1.5 pVNT mean titer (titer dilution−1) |
|---|---|---|---|---|---|---|---|
| Days since AZD7442 administration | |||||||
| 0 | 34.47 | 57.41 | 18.09 | 10.00 | 82.80 | 15.75 | 10.00 |
| 7 | 1704.00 | 627.20 | 178.50 | 656.60 | 453.20 | 163.20 | 62.29 |
| 14 | 5120.00 | 3010.00 | 253.60 | 993.80 | 864.80 | 701.90 | 335.00 |
| 28 | 638.10 | 555.00 | 107.80 | 287.70 | 195.80 | 100.00 | 61.58 |
| 56 | 108.50 | 163.70 | 40.52 | 112.10 | 70.36 | 40.00 | 17.11 |
| 90 | 21.82 | 17.97 | 14.54 | 24.82 | 25.99 | 10.00 | 10.00 |