Table 2.

Model comparison using established methods (control) or following age-matched serum exposure

	Control		Serum Exposure
	Young	Old	Young-Young	Old-Old
Aortic elastic modulus, kPa	4,508 ± 106	7,646 ± 536*	4,906 ± 575	7,386 ± 318*
Preconstriction, %	17 ± 2	16 ± 2	35 ± 2*	40 ± 2*,†
EDD EC50	−7.4 ± 0.5	−7.6 ± 0.8	−6.7 ± 0.5	−7.2 ± 0.5
Peak EDD, %	91 ± 3	71 ± 5*	92 ± 2	73 ± 5*
Peak EID, %	94 ± 1	93 ± 1	97 ± 1	97 ± 1

Values are means ± SE; n = 6–8 mice/group. EDD, endothelium-dependent dilation; EC₅₀, half-maximal effective concentration; EID, endothelium-independent dilation. Statistics are one-way ANOVA. *P < 0.05 vs. young control. †P < 0.05 vs. old control.