Table 3.

Mouse blood electrolytes

	Male	Male	Female	Female
	γWT/WT	γQ4/Q4	γWT/WT	γQ4/Q4
Standard diet
Mice (N)	9	7	12	7
Na+	146 ± 1	146 ± 2	145 ± 2	145 ± 1
K+	4.3 ± 0.2	4.4 ± 0.6	4.1 ± 0.6	4.3 ± 0.4
Cl–	113 ± 3	113 ± 2	113 ± 2	113 ± 3
tCO2	23 ± 2	23 ± 2	22 ± 3	23 ± 2
BUN	29 ± 3	31 ± 4	30 ± 5	28 ± 7
Hb	13.9 ± 0.6	13.8 ± 0.9	13.3 ± 1.0	13.6 ± 1.1
iCa2+	1.27 ± 0.08	1.24 ± 0.09	1.30 ± 0.07	1.34 ± 0.06
Low Na+ diet
Mice (N)	7	7	8	7
Na+	146 ± 1	147 ± 2	147 ± 2	148 ± 2
K+	4.7 ± 0.4	4.2 ± 0.6	4.2 ± 0.2	4.7 ± 0.3
Cl–	117 ± 2	116 ± 3	118 ± 2	118 ± 1
tCO2	21 ± 2	21 ± 1	21 ± 2	21 ± 2
BUN	28 ± 5	26 ± 2	25 ± 5	26 ± 4
Hb	14.1 ± 0.3	14.3 ± 0.4	14.1 ± 0.6	14.6 ± 0.9
iCa2+	1.34 ± 0.04	1.31 ± 0.05	1.32 ± 0.05	1.33 ± 0.07
Aldosteronea	787 ± 189	664 ± 151	789 ± 134	745 ± 256
High K+ diet
Mice (N)	10	7	13	14
Na+	147 ± 2	148 ± 1	147 ± 3	146 ± 2
K+	5.5 ± 1.0	6.1 ± 0.9	6.3 ± 0.7	6.6 ± 0.7
Cl–	120 ± 5	124 ± 1b	121 ± 4	121 ± 4
tCO2	21 ± 2.2	19 ± 1.6	19 ± 2.2	20 ± 0.9
BUN	25 ± 3	25 ± 3	25 ± 5	27 ± 6
Hb	13 ± 1	13 ± 1	13 ± 1	13 ± 1
iCa2+	1.32 ± 0.03	1.32 ± 0.08	1.31 ± 0.06	1.34 ± 0.08

Errors represent standard deviation of the mean. BUN, blood urea nitrogen; Hb, hemoglobin; iCa²⁺, ionized calcium; tCO₂, total carbon dioxide. ^aN for aldosterone measurements = 5 per group. ^bP < 0.05 for comparison with same-sex γ^WT/WT littermate controls by Student’s t test.