Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Aug 26;15:1412513. doi: 10.3389/fimmu.2024.1412513

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2024 Srinivasan, Zhu and McShan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Sequence conservation of CD8α domains across species. Clustal Omega (v1.2.4) alignment (93) of sequences for CD8α from human (UniProt #P01732), mouse (UniProt #P01731), rat (UniProt #P07725), dog (UniProt #P33706), bovine (UniProt #P31783), chicken (UniProt #A0A8V0YYR0), rhesus monkey (UniProt #F7DXK3), and rainbow trout (UniProt #Q9IAL5). The secondary structure of each domain above the sequence is derived from the AlphaFold2 prediction of human CD8α (UniProt AF-P01732-F1). The alignment was processed in ESPript (v3) with domain disambiguation added manually (94). The dots above the sequence highlight the first residue (residue 1) and then every 10 residues after that using the first sequence as a reference.