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. 2024 Aug 26;15:1412513. doi: 10.3389/fimmu.2024.1412513

Figure 3.

Figure 3

Sequence conservation of CD8β domains across species. Clustal Omega (v1.2.4) alignment (93) of sequences for CD8β from human (UniProt #P10966), mouse (UniProt #P10300), rat (UniProt #P05541), dog (UniProt #A0A8C0MNN1), bovine (UniProt #A7YW30), chicken (UniProt #A0A8V0Z0D5), rhesus monkey (UniProt #F7EXY4), and rainbow trout (UniProt #A0A8C7PPI8). The secondary structure of each domain above the sequence is derived from the AlphaFold2 prediction of human CD8β (UniProt AF-P10966-F1). The alignment was processed in ESPript (v3) with domain disambiguation added manually (94). The dots above the sequence highlight the first residue (residue 1) and then every 10 residues after that using the first sequence as a reference.