Table 2.
Summary of anti-CD8 monoclonal antibodies.
| Target | Antibody | Immunomodulatory effect on CD8αβ T cell activation* | Reference(s) |
|---|---|---|---|
| CD8α | YTS 105.18 | blocking | (45) |
| CD8β | YTS 156.7 | blocking | (46) |
| CD8α | ZED8 | neutral | (47) |
| CD8α | VHH5v2 | blocking | (48) |
| CD8α | SK1 | blocking | (49) |
| CD8α | DK25 | blocking | (50, 51) |
| CD8α | 3B5 | blocking | (51) |
| CD8α | MCD8 | neutral or limited blocking | (50, 51) |
| CD8α | CT-CD8a | block | (50–52) |
| CD8β | CT-CD8b | enhance | (50, 51) |
| CD8α | YTS 169.4 | block | (53) |
| CD8β | 53.5.8 | block | (10) |
| CD8α | 2ST8.5H7 | block | (50) |
| CD8α | 53.6.7 | enhance | (50) |
| CD8α | OKT8 | enhance | (50, 51) |
| CD8α | MRC OX-8 | block | (54) |
| CD8β | KT112 | enhance | (50, 55) |
| CD8α | 32/M4 | neutral | (50) |
| CD8α | C8/144B | neutral | (50) |
| CD8α | KT15 | blocking | (52, 55) |
| CD8α | H59.101 | blocking | (52) |