Table 3. Medios AI-AMD diagnosis versus ophthalmologist diagnosis.

AMD diagnosis	Medios AI-AMD for target device
	Validation set		Test set
	Non-referable AMD	Referable AMD	Non-referable AMD	Referable AMD
Ophthalmologist grading*
No AMD	104	12	105	10
Early AMD	20	6	18	7
Non-referable†	12	5	10	8
Intermediate
AMD	4	32	5	35
Advanced AMD	5	31	†	32
Referable‡	*	6	0	6
Diagnostic accuracy, %
Recall No AMD	89.66(95% CI: 82.6 to 94.5)		91.30(95% CI: 84.6 to 95.8)
Recall Early AMD	76.92(95% CI: 56.4 to 91.0)		72.00(95% CI: 50.6 to 87.9)
Recall Intermediate AMD		88.89(95% CI: 73.9 to 96.9)		87.50(95% CI: 73.2 to 95.8)
Recall Advanced AMD		86.11(95% CI: 70.5 to 95.3)		94.12(95% CI: 80.3 to 99.3)

^*Ground Ttruth.

^†No consensus, but 2two out 3three ophthalmologists graded non-referable.

^‡No consensus, but 2two out 3three ophthalmologists graded referable.

AIartificial intelligenceAMDage-related macular degeneration