Table 1.
Plaque Outcomes by hs-cTnT Level
| All Participants |
|||||||
|---|---|---|---|---|---|---|---|
| Total (N = 708) | <6 ng/L (n = 276) | 6-7.52 ng/L (n = 143) | 7.52-9.63 ng/L (n = 143) | 9.64 ng/L+ (n = 146) | P Value | ||
| Participants with plaque presenta | Yes | 341 (48%) | 106 (38%) | 71 (50%) | 75 (52%) | 89 (61%) | <0.0001 |
| Plaque with visible noncalcified portiona | Yes | 277 (39%) | 82 (30%) | 59 (41%) | 62 (43%) | 74 (51%) | <0.0001 |
| Number of visible noncalcified segmentsb | 0 | 431 (61%) | 194 (70%) | 84 (59%) | 81 (57%) | 72 (49%) | <0.0001 |
| 1-2 | 226 (32%) | 67 (24%) | 50 (35%) | 52 (36%) | 57 (39%) | - | |
| >=3 | 51 (7%) | 15 (5%) | 9 (6%) | 10 (7%) | 17 (12%) | - | |
| Plaque with vulnerable featuresa | Yes | 155 (22%) | 41 (15%) | 33 (23%) | 37 (26%) | 44 (30%) | 0.0001 |
| Low attenuation plaque | Yes | 41 (6%) | 9 (3%) | 8 (6%) | 9 (6%) | 15 (10%) | - |
| Napkin ring sign | Yes | 21 (3%) | 8 (3%) | 3 (2%) | 3 (2%) | 7 (5%) | - |
| Positive remodeling | Yes | 150 (21%) | 40 (14%) | 31 (22%) | 36 (25%) | 43 (29%) | - |
| Plaque with noncalcified portion or plaque with vulnerable featuresa | Yes | 292 (41%) | 88 (32%) | 62 (43%) | 64 (45%) | 78 (53%) | <0.0001 |
| Calcium score (Agatston)a | >0 | 234 (35%) | 75 (28%) | 52 (38%) | 45 (33%) | 62 (45%) | 0.003 |
| # missing | 33 | 12 | 6 | 7 | 8 | - | |
| Among those with CAC > 100 | 1-100 | 166 (71%) | 60 (80%) | 38 (73%) | 34 (76%) | 34 (55%) | 0.150 |
| 101-400 | 56 (24%) | 11 (15%) | 11 (21%) | 10 (22%) | 24 (39%) | - | |
| >400 | 12 (5%) | 4 (5%) | 3 (6%) | 1 (2%) | 4 (6%) | - | |
| Calcium score (Agatston) (all groups)b | 0 | 441 (65%) | 189 (72%) | 85 (62%) | 91 (67%) | 76 (55%) | 0.0002 |
| 1-100 | 166 (25%) | 60 (23%) | 38 (28%) | 34 (25%) | 34 (25%) | - | |
| 101-400 | 56 (8%) | 11 (4%) | 11 (8%) | 10 (7%) | 24 (17%) | - | |
| >400 | 12 (2%) | 4 (2%) | 3 (2%) | 1 (1%) | 4 (3%) | - | |
| Leaman score categoryb | 0 | 367 (53%) | 170 (63%) | 72 (51%) | 68 (48%) | 57 (40%) | <0.0001 |
| >0-5 | 225 (32%) | 74 (27%) | 51 (36%) | 53 (37%) | 47 (33%) | - | |
| >5 | 105 (15%) | 28 (10%) | 18 (13%) | 21 (15%) | 38 (27%) | - | |
| Maximum stenosisb | 0% | 367 (53%) | 170 (63%) | 72 (51%) | 68 (48%) | 57 (40%) | <0.0001 |
| 1%-49% | 308 (44%) | 95 (35%) | 68 (48%) | 71 (50%) | 74 (52%) | - | |
| 50%-69% | 15 (2%) | 3 (1%) | 1 (1%) | 3 (2%) | 8 (6%) | - | |
| 70%-100% or ≥50% left main | 7 (1%) | 4 (1%) | 0 (0%) | 0 (0%) | 3 (2%) | - | |
| # missing | 11 | 4 | 2 | 1 | 4 | - | |
Bold text indicates significant P values.
CAC = coronary artery calcium; hs-cTnT = high-sensitivity cardiac troponin.
a
Cochran-Armitage trend test.
b
Linear-by-linear association test.