Table 2.

Applications of hydrolyzed collagen (HC) as a functional supplement and its impact on the skin, modified from (León-López et al., 2019).

Product	Functionality	Duration	References
HC oral supplementation extracted from catfish skin	Enhance skin hydration, suppleness, and wrinkling.	(Tested on women 40–60 years old for 12 weeks).	[49]
Oral nutrient supplement with HC	Improved firmness, elasticity, and dermal thickness.	(Tested on women aged 35 to 65 for triple of months.	[50]
Fish-extracted oral HC supplement	Improve skin elasticity and texture, and maintains the health of joints	(Tested on 120 individuals for triple of months).	[51]
Fish-extracted oral HC supplement	Increase collagen density and moisture in the dermis	(Tested on women aged 40 to 59).	[52]
HC oral supplement with Vitamins E, C, A and zinc	Improve the firmness, elasticity, texture, and hydration of the skin	(Tested on women between the ages of 40 and 50 for 28 days).	[53]
HC drink	Development in the elasticity, moisture, and periorbital wrinkles of the skin	(Tested on healthy women between the ages of 30 and 60).	[54]
HC ampoules prepared with acerola fruit extract, vitamin C and E with zinc, and biotin	Elasticity, roughness, hydration, and density of the skin are improved	After 12 weeks of oral supplementation.	[55]